FURIN 蛋白
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- 抗原 See all FURIN 蛋白
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Hi-5 Cells
- 序列
- DLNVKAAWAQ GYTGHGIVVS ILDDGIEKNH PDLAGNYDPG ASFDVNDQDP DPQPRYTQMN DNRHGTRCAG EVAAVANNGV CGVGVAYNAR IGGVRMLDGE VTDAVEARSL GLNPNHIHIY SASWGPEDDG KTVDGPARLA EEAFFRGVSQ GRGGLGSIFV WASGNGGREH DSCNCDGYTN SIYTLSISSA TQFGNVPWYS EACSSTLATT YSSGNQNEKQ IVTTDLRQKC TESHTGTSAS APLAAGIIAL TLEANKNLTW RDMQHLVVQT SKPAHLNAND WATNGVGRKV SHSYGYGLLD AGAMVALAQN WTTVAPQRKC IIDILTEPKD IGKRLEVRKT VTACLGEPNH ITRLEHAQAR LTLSYNRRGD LAIHLVSPMG TRSTLLAARP HDYSADGFND WAFMTTHSWD EDPSGEWVLE IENTSEANNY GTLTKFTLVL YGTAPEGLPV PPESSGCKTL TSSQACVVCE EGFSLHQKSC VQHCPPGFAP QVLDTHYSTE NDVETIRASV CAPC
- 产品特性
- Biological activity was measured by its ability to cleave the fluorogenic peptide substrate Boc-Arg-Val-Arg-Arg-AMC (Bachem Catalog# I-1645.0025).
- 纯度
- < 95 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product FURIN 蛋白
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Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 28-794) protein (GST tag)
FURIN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 108-371) protein (His-IF2DI Tag)FURIN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 27-574) protein (His tag)FURIN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 1-148) proteinFURIN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing Furin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Furin stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
- 别名
- Furin (FURIN 产品)
- 别名
- FURIN Protein, furin Protein, si:dkey-281a24.5 Protein, FUR Protein, LOC100220259 Protein, PACE Protein, spc1 Protein, xfurin Protein, MGC82710 Protein, PCSK3 Protein, SPC1 Protein, 9130404I01Rik Protein, Fur Protein, Pcsk3 Protein, Pace Protein, furin, paired basic amino acid cleaving enzyme Protein, furin (paired basic amino acid cleaving enzyme) a Protein, furin (paired basic amino acid cleaving enzyme) b Protein, furin, paired basic amino acid cleaving enzyme L homeolog Protein, furin (paired basic amino acid cleaving enzyme) Protein, FURIN Protein, furina Protein, furinb Protein, furin Protein, furin.L Protein, Furin Protein
- 背景
- Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Furin is a calcium dependent serine endoprotease that processes numerous proproteins of different secretory pathways into their mature forms by cleaving at the carboxyl side of the recognition sequence, R-Xaa-(K/R)-R, where Xaa can be any amino acid. Recombinant human Furin is a 63.9 kDa protein, corresponding to residues 131 through 715 of the Furin precursor plus a C-terminal His tag.
- 基因ID
- 5045
- NCBI登录号
- NP_001276752
- OMIM
- 577019578
- UniProt
- P09958
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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