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Calreticulin Protein (CALR) (AA 18-417)
CALR
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
~90 %
WB, ELISA, MS
产品细节
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抗原
See all Calreticulin (CALR) 蛋白
Calreticulin (CALR)
蛋白类型
Recombinant
产品特性
AA 18-417
宿主
All origins for Calreticulin 蛋白
人
资源
All sources for Calreticulin 蛋白
大肠杆菌(E. Coli)
应用范围
Western Blotting (WB), ELISA, Mass Spectrometry (MS)
纯度
~90 %
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Alternatives
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使用细节
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应用备注
This recombinant protein can be used for WB, ELISA, MS.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
10 mM Tris, pH 8.0, 0.002 % NaN, 3 mM NaCl, 2.5 mM
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
储存条件
-80 °C
储存方法
Store in working aliquots at -70 °C.
目标详细情况
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Calreticulin (CALR)
别名
CALR (CALR 产品 )
别名
CRT Protein, RO Protein, SSA Protein, cC1qR Protein, crc Protein, crt Protein, Calregulin Protein, CG9429 Protein, Clr Protein, Dmel\\CG9429 Protein, anon-EST:Liang-2.11 Protein, anon-EST:Liang-2.17 Protein, anon-EST:fe3D7 Protein, clone 2.11 Protein, clone 2.17 Protein, eth Protein, potp Protein, cc1qr Protein, ssa Protein, NV19007 Protein, CRP55 Protein, ERp60 Protein, HACBP Protein, CHOT1 Protein, CHT1 Protein, CT1 Protein, AA589632 Protein, CRTR Protein, Creat Protein, CCDS1 Protein, calrl2 Protein, fc66d10 Protein, wu:fc66d10 Protein, wu:fj50c03 Protein, zgc:66153 Protein, calreticulin Protein, calreticulin L homeolog Protein, Calreticulin Protein, putative calreticulin Protein, solute carrier family 6 member 8 Protein, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Protein, CALR Protein, calr.L Protein, Crt Protein, crt Protein, CRT Protein, Calr Protein, calr Protein, LMJF_31_2600 Protein, Crc Protein, Slc6a8 Protein, SLC6A8 Protein, LOC8269812 Protein
背景
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
分子量
46 kDa (Calculated)
基因ID
811
NCBI登录号
NP_004334
OMIM
4757900
UniProt
P27797
途径
Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Nuclear Hormone Receptor Binding , ER-Nucleus Signaling , Unfolded Protein Response
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