BMP5 蛋白
This Recombinant BMP5 protein is expressed in CHO Cells.
Quick Overview for BMP5 蛋白 (ABIN2468294)
抗原
See all BMP5 蛋白
BMP5
(Bone Morphogenetic Protein 5 (BMP5))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
CHO Cells
纯度
< 95 % by SDS-PAGE gel and HPLC analyses.
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序列
- AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
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产品特性
- Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 μg/mL.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Bone Morphogenetic Protein 5 (BMP5) (AA 1-454) protein (GST tag)
BMP5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 5 (BMP5) (AA 317-454) proteinBMP5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing BMP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
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别名
- BMP-5
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背景
- TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
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基因ID
- 653
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NCBI登录号
- NP_066551
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OMIM
- 10835091
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UniProt
- P22003
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
抗原
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