As with any protein, exposing BMP-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
储存条件
-20 °C
储存方法
The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-3 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
BMP-3A Protein, PBMP3 Protein, 9130206H07 Protein, 9530029I04Rik Protein, BMP3 Protein, BMP-3 Protein, wu:fk96e01 Protein, zgc:153939 Protein, xBMP-3 Protein, bone morphogenetic protein 3 Protein, bone morphogenetic protein 3 L homeolog Protein, BMP3 Protein, Bmp3 Protein, bmp3 Protein, bmp3.L Protein
背景
TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-3 is abundantly found in adult bone, and to a lesser extent fetal cartilage. BMP-3 inhibits osteogenesis and bone formation by activating a signaling cascade that antagonizes the signaling of pro-osteogenic BMPs. Recombinant human BMP-3 is a disulfide linked homodimeric protein that corresponds to residues 361 to 472 of the 472 amino acid BMP-3 precursor protein.