RAD51 蛋白
RAD51
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as judged from SDS-PAGE analysis
Func
Active
1 image
(2 references)-
- 抗原 See all RAD51 蛋白
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func)
- 产品特性
- This product was confirmed to possess single strand DNA stimulated ATPase activity.
- 纯度
- > 95 % as judged from SDS-PAGE analysis
- Top Product
- Discover our top product RAD51 蛋白
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DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) protein (GST tag)
RAD51 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
DNA Repair Protein Homolog 1 (RAD51) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RAD51 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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1) Studies on homologous recombination in mammals including human
2) Studies on the interaction of Rad51 protein with various proteins
3) To be used as a standard for Western blotting - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 20 mM Tris-HCl pH 8.0, 100 mM KCl, 1 mM DTT, 0.5 mM EDTA, 10 % glycerol
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Store at -80 C for long period.
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: "Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases." in: Nature, Vol. 451, Issue 7181, pp. 1018-21, (2008) (PubMed).
: "Human Rad51 amino acid residues required for Rad52 binding." in: Journal of molecular biology, Vol. 291, Issue 3, pp. 537-48, (1999) (PubMed).
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: "Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases." in: Nature, Vol. 451, Issue 7181, pp. 1018-21, (2008) (PubMed).
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- 抗原
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
- 别名
- Rad51 (RAD51 产品)
- 别名
- BRCC5 Protein, HRAD51 Protein, HsRad51 Protein, HsT16930 Protein, MRMV2 Protein, RAD51A Protein, RECA Protein, CRAD51 Protein, wu:fb38e12 Protein, zgc:77754 Protein, RGD1563603 Protein, ATRAD51 Protein, F22D1.20 Protein, F22D1_20 Protein, RAS associated with diabetes protein 51 Protein, AV304093 Protein, Rad51a Protein, Reca Protein, brcc5 Protein, rad51 Protein, rad51a Protein, reca Protein, xrad51 Protein, RAD51 recombinase Protein, RAS associated with diabetes protein 51 Protein, RAD51 recombinase L homeolog Protein, RAD51 Protein, rad51 Protein, Rad51 Protein, rad51.L Protein
- 背景
- Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogene proteins and tumor suppressors such as BRCA1, BRCA2, and P53 for the maintenance of genome stability. Rad51 protein was highly purified from E. coli over-expressing human Rad51 protein as a recombinant protein. Since the tag was removed from the recombinant protein (it still contains Gly-Ser-His at the N-terminal), it has been shown to retain nuclear filament forming and strand-exchange activity as well as interaction with Rad52.
- UniProt
- Q06609
- 途径
- DNA Damage Repair
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