VEGF Protein (AA 27-191) (Biotin)
(1 reference)-
- 抗原 See all VEGF 蛋白
- VEGF (Vascular Endothelial Growth Factor (VEGF))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-191
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This VEGF protein is labelled with Biotin.
- 品牌
- MABSol®,UltraLys
- 序列
- AA 27-191
- 特异性
- The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
- 产品特性
- The product does NOT contain any epitope tags. The protein has a calculated MW of 19 kDa (monomer). The protein migrates as 24 kDa (monomer) on a SDS-PAGE gel under reducing (R) condition due to glycosylation and 43-50 kDa under non-reducing (NR) condition.
- 纯度
- >95 % as determined by reduced SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product VEGF 蛋白
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Vascular Endothelial Growth Factor (VEGF) (AA 27-191) (Active) protein
HPLC verified VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (Active) proteinVEGF 宿主: 人 宿主: Yeast (Pichia pastoris) > 95 % by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-191) (Active) protein (His tag)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-190) (Active) proteinHPLC verified VEGF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-147) (Active) protein (AVI tag,His tag,Biotin)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (Active) proteinVEGF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Vascular Endothelial Growth Factor (VEGF) (AA 205-324) protein (His tag)VEGF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Vascular Endothelial Growth Factor (VEGF) (AA 27-147) (Active) protein (His tag)VEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Vascular Endothelial Growth Factor (VEGF) (AA 27-146) (Active) proteinVEGF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 说明
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A chemically labeled biotinylated protein with ultra sensitivity.
The product is produced using a chemical labeling approach. The primary amines in the side chains of lysine residues and the N-terminus of protein are conjugated with biotins.
Chemical labeling usually results in multiple biotin attachment on a single protein molecule, which could potentially lead to higher detection sensitivity. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "Neuropilin-1 drives tumor-specific uptake of chlorotoxin." in: Cell communication and signaling : CCS, Vol. 17, Issue 1, pp. 67, (2019) (PubMed).
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: "Neuropilin-1 drives tumor-specific uptake of chlorotoxin." in: Cell communication and signaling : CCS, Vol. 17, Issue 1, pp. 67, (2019) (PubMed).
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- 抗原
- VEGF (Vascular Endothelial Growth Factor (VEGF))
- 别名
- VEGF (VEGF 产品)
- 别名
- MVCD1 Protein, VEGF Protein, VPF Protein, Vegf Protein, Vegf120 Protein, Vegf164 Protein, Vegf188 Protein, Vpf Protein, VEGF-A Protein, VEGF164 Protein, eVEGF120 Protein, eVEGF164 Protein, vegf-a Protein, vegf Protein, vascular endothelial growth factor A Protein, vascular endothelial growth factor A L homeolog Protein, vascular endothelial growth factor Protein, vascular endothelial growth factor precursor Protein, VEGFA Protein, Vegfa Protein, vegfa.L Protein, VEGF Protein, vegf Protein
- 背景
- VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.
- 分子量
- 19.2 kDa
- NCBI登录号
- NP_001165097
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