This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.3 kDa. As a result of glycosylation, the protein migrates as 80-90 kDa under reducing (R) condition, and 160-180 kDa under non-reducing (NR) condition (SDS-PAGE).
SIGLEC6
宿主: 人
宿主: HEK-293 Cells
Recombinant
>92 % as determined by SDS-PAGE.
WB
Active
限制
仅限研究用
状态
Lyophilized
缓冲液
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5
注意事项
Please avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.