FLT3 is a receptor tyrosine kinase with important roles in hematopoietic stem/progenitor cell survival and proliferation. It is mutated in about 1/3 of acute myeloid leukemia (AML) patients, either by internal tandem duplications (ITD) of the juxtamembrane domain or by point mutations usually involving the kinase domain (kDa). Alternative Names: Flt3, FLT3 protein, Flt-3, Flt-3 ligand, Fms-related tyrosine kinase 3 ligand protein, Flt-3 protein, Flt 3, Flt-3 protein, Flt 3 protein