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CCL5 Protein (AA 24-91)

CCL5 宿主: 人 宿主: HEK-293T Cells Recombinant > 98 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018332
发货至: 中国
  • 抗原 See all CCL5 蛋白
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-91
    宿主
    • 17
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    资源
    • 27
    • 8
    • 2
    • 2
    • 1
    • 1
    HEK-293T Cells
    产品特性
    The EC50 value of human RANTES/CCL5 on Ca2+ mobilization assay in CHO-K1/G alpha 15/hCCR1 cells (human G alpha 15 and human CCR1 stably expressed in CHO-K1 cells) is less than 0.2 μg/mL.
    纯度
    > 98 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product CCL5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human RANTES/CCL5 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human RANTES/CCL5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C
    有效期
    6 months
  • 抗原
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    别名
    RANTES (CCL5) (CCL5 产品)
    别名
    Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
    背景
    Chemokine (C-C motif) ligand 5(CCL5), also known as RANTES (Regulated upon activation, Normal T cell Expressed and presumable Secreted) is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. RANTES is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes in inflammatory sites. With the help of specific cytokines (i.e., IL-2 and IFN-gamma) that are released by T cells, RANTES induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells. RANTES is also an HIV-suppressive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans. It has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).Recombinant human RANTES/CCL5 produced in HEK293 cells is a single polypeptide chain containing 68 amino acids. A fully biologically active molecule, rhRANTES/CCL5 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
    Synonyms: RANTES/CCL5, Human
    分子量
    8 kDa, observed by reducing SDS-PAGE.
    UniProt
    P13501
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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