Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
IEGF Protein, SCDGF-B Protein, SCDGFB Protein, Scdgfb Protein, rSCDGF-B Protein, PDGFD Protein, 1110003I09Rik Protein, platelet derived growth factor D Protein, platelet-derived growth factor, D polypeptide Protein, PDGFD Protein, Pdgfd Protein
背景
PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing. Synonyms: platelet-derived growth factor D, IEGF, SCDGFB