Neurotrophin 4 Protein (NTF4) (AA 81-210)
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- 抗原 See all Neurotrophin 4 (NTF4) 蛋白
- Neurotrophin 4 (NTF4)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 81-210
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
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ED50 < 5.0 μg/mL, measured by a cell proliferation assay using C6 cells, corresponding to a specific activity of > 2.0x 102 units/mg.
AA 81-210, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- < 0.3 EU/μg, determined by LAL method.
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Neurotrophin 4 (NTF4) (AA 81-210) protein
NTF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Neurotrophin 4 (NTF4) (AA 1-210) protein (GST tag)NTF4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neurotrophin 4 (NTF4) (AA 111-209) protein (GST tag)NTF4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neurotrophin 4 (NTF4) (AA 82-210) protein (His tag)NTF4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Neurotrophin 4 (NTF4) proteinNTF4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in 50 mM acetic acid or ddH2O at 50 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 50 mM acetic acid.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Neurotrophin-4 (rhNT-4) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhNT-4 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- Neurotrophin 4 (NTF4)
- 别名
- Neurotrophin-4 (NT-4) (NTF4 产品)
- 别名
- NTF5 Protein, GLC10 Protein, GLC1O Protein, NT-4 Protein, NT-4/5 Protein, NT-5 Protein, NT4 Protein, NT5 Protein, NT4P Protein, Ntf5 Protein, 2900040K06Rik Protein, AI462899 Protein, NT4/5 Protein, Ntf-5 Protein, Ntf4 Protein, neurotrophin 4 Protein, neurotrophin 5 Protein, NTF4 Protein, Ntf4 Protein, ntf4 Protein, Ntf5 Protein
- 背景
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Neurotrophin-4 (NT-4), also known as NT-5, is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-3. Human NT-4 shares 48 - 52 % aa sequence identity with human beta-NGF, BDNF, and NT-3.Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds. NT-4 is expressed highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 can signal through TrkB receptors and promotes the survival of peripheral sensory sympathetic neurons.Recombinant human Neurotrophin-4 (rhNT-4) produced in E.coli is a noncovalently linked homodimer containing two non-glycosylated polypeptide chains of 131 amino acids. A fully biologically active molecule, rhNT-4 has a molecular mass of 28.1 kDa analyzed by reducing SDS-PAGE.
Synonyms: Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5) - 分子量
- 28.1 kDa, a noncovalently linked homodimer,of two 14.0 kDa polypeptide monomers.
- UniProt
- P34130
- 途径
- RTK signaling
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