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NOV Protein (AA 32-357)

NOV 宿主: 人 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018276
发货至: 中国
  • 抗原 See all NOV 蛋白
    NOV (Nephroblastoma Overexpressed (NOV))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 32-357
    宿主
    • 6
    • 3
    • 2
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
    • 2
    • 1
    CHO Cells
    产品特性
    ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product NOV 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Human NOV remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human NOV should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    NOV (Nephroblastoma Overexpressed (NOV))
    别名
    Nephroblastoma Overexpressed Gene Protein (NOV) (NOV 产品)
    别名
    CCN3 Protein, IBP-9 Protein, IGFBP-9 Protein, IGFBP9 Protein, NOVh Protein, nov-A Protein, xnov Protein, NovH Protein, C130088N23Rik Protein, nephroblastoma overexpressed Protein, nephroblastoma overexpressed L homeolog Protein, nephroblastoma overexpressed gene Protein, NOV Protein, nov.L Protein, Nov Protein
    背景
    Nephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
    Synonyms: Nephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
    分子量
    20-50 kDa, observed by reducing SDS-PAGE.
    UniProt
    P48745
    途径
    Smooth Muscle Cell Migration, Growth Factor Binding
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