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CCL2 Protein (AA 24-148)

CCL2 宿主: 大鼠 宿主: HEK-293T Cells Recombinant > 98 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018224
发货至: 中国
  • 抗原 See all CCL2 蛋白
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-148
    宿主
    • 18
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    大鼠
    资源
    • 32
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    HEK-293T Cells
    产品特性
    The EC50 value of rat MCP-1/CCL2 on Ca2+ mobilization assay in CHO-K1/G alpha 15/rCCR2 cells (human G alpha 15 and rat CCR2 stably expressed in CHO-K1 cells) is less than 0.3 μg/mL.
    纯度
    > 98 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product CCL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Rat MCP-1/CCL2 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat MCP-1/CCL2 should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    别名
    MCP-1/CCL2 (CCL2 产品)
    别名
    GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein
    背景
    Chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemotactic protein 1 (MCP1) and small inducible cytokine A2. CCL2 is a small cytokine that belongs to the CC chemokine family. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. CCL2 is implicated in the pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis. CCL2 is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. CCL2 is primarily secreted by monocytes, macrophages and dendritic cells. CCL2 can signal through the CCR2 receptor.Recombinant rat MCP-1/CCL2 produced in HEK293 cells is a polypeptide chain containing 125 amino acids. A fully biologically active molecule, rrMCP-1/CCL2 has a molecular mass of 10-15 kDa analyzed by reducing SDS-PAGE.
    Synonyms: MCP-1, MCAF, JE, Monocyte Chemotactic Protein-1 (MCP-1), CCL2
    分子量
    10-15 kDa, observed by reducing SDS-PAGE.
    UniProt
    P14844
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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