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IL-6 Protein (AA 29-212)

IL6 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analysis. Active
产品编号 ABIN2018139
发货至: 中国
  • 抗原 See all IL-6 (IL6) 蛋白
    IL-6 (IL6) (Interleukin 6 (IL6))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 29-212
    宿主
    • 26
    • 16
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 4
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    资源
    • 44
    • 24
    • 19
    • 5
    • 4
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    • 1
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    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 <0.1 ng/mL, measured by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells, corresponding to a specific activity of > 1 x 10^7 units/mg.
    AA 29-212, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE analysis.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against 1xPBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Interleukin-6 (rhIL-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-6 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    Interleukin-6 (IL-6) (IL6 产品)
    别名
    BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
    背景
    Interleukin-6 (IL-6, also known as IFN-beta2) is a pleiotropic cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 is secreted by T cells and macrophages to stimulate immune response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone marrow. It supports the growth of B cells and is antagonistic to regulatory T cells.Recombinant human Interleukin-6 (rhIL-6) produced in E. coli is a single non-glycosylated polypeptide chain containing 185 amino acids. A fully biologically active molecule, rhIL-6 has a molecular mass of 20.9 kDa analyzed by reducing SDS-PAGE.
    Synonyms: 26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
    分子量
    20.9 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q75MH2
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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