IL-18 Protein (AA 37-194)
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- 抗原 See all IL-18 (IL18) 蛋白
- IL-18 (IL18) (Interleukin 18 (IL18))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 37-194
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宿主
- 大鼠
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资源
- 大肠杆菌(E. Coli)
- 产品特性
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ED50 <2 μg/mL resulted in the secretion of 0.15 ng/mL h-IFN-gamma when tested using KG-1 cell line, corresponding to a specific activity of > 500 units/mg.
AA 37-194, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE analyses.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL18 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against 50 mM Tris, 50 mM NaCl, pH 8.0.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant ratInterleukin-18 (rrIL-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrIL-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- IL-18 (IL18) (Interleukin 18 (IL18))
- 别名
- Interleukin-18 (IL-18) (IL18 产品)
- 别名
- Igif Protein, Il-18 Protein, IL-18 Protein, IGIF Protein, ChIL-18 Protein, IL-1g Protein, IL1F4 Protein, IL18 Protein, interleukin 18 Protein, Il18 Protein, IL18 Protein
- 背景
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Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.Recombinant rat Interleukin-18 (rrIL-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 159 amino acids. A fully biologically active molecule, rrIL-18 has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE.
Synonyms: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Interferon-gamma-inducing factor, IGIF, IL-1g, IL1F4, IL-1 gamma - 分子量
- 18.4 kDa, observed by reducing SDS-PAGE.
- 途径
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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