IL-11 Protein (AA 23-199)
-
- 抗原 See all IL-11 (IL11) 蛋白
- IL-11 (IL11) (Interleukin 11 (IL11))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-199
-
宿主
- 小鼠
-
资源
- HEK-293T Cells
- 产品特性
- ED50 < 3 ng/mL, measured in a cell proliferation assay using T11 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL11 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
-
- 抗原
- IL-11 (IL11) (Interleukin 11 (IL11))
- 别名
- Interleukin-11(IL-11) (IL11 产品)
- 背景
-
Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1alpha-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
Synonyms: IL-11 - 分子量
- 21 kDa, observed by reducing SDS-PAGE.
- UniProt
- P47873
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
-