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FGF9 Protein (AA 3-208, Ser34Asn-Mutant)

FGF-9 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2017840
发货至: 中国
  • 抗原 See all FGF9 (FGF-9) 蛋白
    FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 3-208, Ser34Asn-Mutant
    宿主
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    小鼠
    资源
    • 20
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 < 5 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 2x10^5 units/mg.
    AA 3-208 (Ser34Asn), expressed with an N-terminal Met.
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF-9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouse Fibroblast Growth Factor (rmFGF-9) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmFGF-9 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    FGF9 (FGF-9) (Fibroblast Growth Factor 9 (FGF-9))
    别名
    Fibroblast Growth Factor-9 (FGF-9) (FGF-9 产品)
    别名
    Eks Protein, FGF-9 Protein, GAF Protein, HBFG-9 Protein, HBGF-9 Protein, SYNS3 Protein, XFGF-9 Protein, fgf9-A Protein, fibroblast growth factor 9 Protein, fibroblast growth factor 9 S homeolog Protein, Fgf9 Protein, FGF9 Protein, fgf9.S Protein
    背景
    Fibroblast Growth Factor-9 (FGF-9) is a pleiotropic cytokine and belongs to the heparin-binding FGF family. Like other members in the family, FGF-9 resembles a beta-trefoil structure. FGF-9 undergoes reversible dimerization, a common characteristic shared by its subfamily members, FGF-16 and FGF-20. The mutations involved in the homodimerization also affect the affinity for heparin, binding to FGF receptors, and biological activity. In vivo, FGF-9 is expressed in limb buds, the developing skeleton, and in the intestines during late stage embryogenesis. FGF-9 is essential for the development of heart, lung, kidney, cecum, and testes, and the reduction of FGF-9 level leads to premature differentiation. FGF-9 also works along with Bone Morphogenetic Protein-7 (BMP-7) to promote the survival of nephron progenitors.Recombinant mouse Fibroblast Growth Factor (rmFGF-9) produced in E. coli is a single non-glycosylated polypeptide chain containing 207 amino acids. A fully biologically active molecule, rmFGF-9 has a molecular mass of 23.4 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Growth Factor-9, GAF (Glia-activating factor), HBGF-9
    分子量
    23.4 kDa, observed by reducing SDS-PAGE.
    UniProt
    P54130
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