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FGF8 Protein (AA 23-215)

FGF8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN2017830
发货至: 中国
  • 抗原 See all FGF8 蛋白
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 23-215
    宿主
    • 8
    • 3
    • 2
    • 1
    • 1
    资源
    • 13
    • 2
    大肠杆菌(E. Coli)
    产品特性
    ED50 < 5.0 ng/mL, measured by a cell proliferation assay using 3T3 cells in the presence of 1 μg/mL of heparin, corresponding to a specific activity of > 2.0x 10^5 units/mg.
    AA 23-215, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Fibroblast Growth Factor-8 (rhFGF-8) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-8 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    别名
    Fibroblast Growth Factor-8 (FGF-8) (FGF8 产品)
    别名
    Aigf Protein, Fgf-8 Protein, AIGF Protein, FGF-8 Protein, HBGF-8 Protein, HH6 Protein, KAL6 Protein, fibroblast growth factor 8 Protein, Fgf8 Protein, FGF8 Protein
    背景
    Fibroblast Growth Factor-8 (FGF-8) is a heparin-binding growth factor of the FGF family. There are 4 known forms of FGF8 produced by alternative splicing: FGF8a, FGF-8b, FGF-8e and FGF-8f. The human and mouse FGF8b are identical of aa sequences. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF-8 is required for normal brain, eye, ear and limb development during embryogenesis. It is also required for normal development of the gonadotropin- releasing hormone (GnRH) neuronal system.Recombinant human Fibroblast Growth Factor-8 (rhFGF-8) produced in E. coli is a single non-glycosylated polypeptide chain containing 194 amino acids. A fully biologically active molecule, rhFGF-8 has a molecular mass of 22.5 kDa analyzed by reducing SDS-PAGE.
    Synonyms: FGF-8b, AIGF, HBGF
    分子量
    22.5kDa, observed by reducing SDS-PAGE.
    UniProt
    P55075
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
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