FAS Protein (AA 26-172)
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- 抗原 See all FAS 蛋白
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 26-172
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宿主
- 人
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资源
- HEK-293T Cells
- 产品特性
- ED50 <0.4 μg/mL, measured by its ability to inhibit the cytotoxicity of Jurkat cells in the presence of 20 ng/mL of human Fas Ligand.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product FAS 蛋白
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TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (Fc Tag)
FAS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) protein (Fc Tag)FAS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (His tag)FAS 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
TNF Receptor Superfamily, Member 6 (FAS) (AA 25-169) protein (His-DYKDDDDK-Strep II Tag)FAS 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (Fc Tag)FAS 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TNF Receptor Superfamily, Member 6 (FAS) protein (His tag)FAS 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
TNF Receptor Superfamily, Member 6 (FAS) (AA 17-173) protein (His tag)FAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) protein (GST tag)FAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) protein (GST tag)FAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Human Fas Receptor remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Fas Receptor should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- 有效期
- 6 months
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- 抗原
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- 别名
- Fas Receptor (FAS 产品)
- 别名
- ALPS1A Protein, APO-1 Protein, APT1 Protein, CD95 Protein, FAS1 Protein, FASTM Protein, TNFRSF6 Protein, AI196731 Protein, APO1 Protein, TNFR6 Protein, Tnfrsf6 Protein, lpr Protein, Fas cell surface death receptor Protein, Fas (TNF receptor superfamily member 6) Protein, FAS Protein, Fas Protein, fas Protein
- 背景
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Fas Receptor and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor that serves as a sink for FasL.
Synonyms: soluble Fas receptor (sFasR), TNFRSF6, CD95, Apo I, Fas Antigen - 分子量
- 17-29 kDa, observed by reducing SDS-PAGE.
- NCBI登录号
- NP_000034
- 途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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