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EGF Protein (AA 974-1026)

EGF 宿主: 大鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2017760
发货至: 中国
  • 抗原 See all EGF 蛋白
    EGF (Epidermal Growth Factor (EGF))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 974-1026
    宿主
    • 21
    • 13
    • 7
    • 4
    • 3
    • 1
    大鼠
    资源
    • 31
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    产品特性
    ED50 < 0.1 ng/mL, measured in a cell proliferation assay using 3T3 cells.
    纯度
    > 95 % as analyzed by SDS-PAGE and HPLC.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product EGF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Rat Epidermal Growth Factor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Rat Epidermal Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    EGF (Epidermal Growth Factor (EGF))
    Abstract
    EGF 产品
    别名
    HOMG4 Protein, URG Protein, AI790464 Protein, CEGF Protein, epidermal growth factor Protein, pro-epidermal growth factor Protein, EGF Protein, egf Protein, CpipJ_CPIJ020278 Protein, Egf Protein
    背景
    Epidermal Growth Factor, a low-molecular-weight polypeptide, is the founding member of the EGF-family of proteins. It can be found in platelets, macrophages, urine, saliva, etc. EGF acts by binding with high affinity to the Epidermal Growth Factor Receptor (EGFR) and stimulating downstream protein tyrosine kinase activity. This signal transduction cascade results in increased intracellular calcium levels and increased rates of glycolysis and protein synthesis. EGF stimulates the growth of many epidermal and epithelial tissues. Pharmaceutical drugs designed to inhibit EGFR have been used to treat certain types of cancer.
    Synonyms: Epidermal Growth Factor, Urogastrone, URG
    分子量
    6 kDa, observed by reducing SDS-PAGE.
    UniProt
    P07522
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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