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EGF Protein (AA 977-1029)

EGF 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE and HPLC analysis. Active
产品编号 ABIN2017757
发货至: 中国
  • 抗原 See all EGF 蛋白
    EGF (Epidermal Growth Factor (EGF))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 977-1029
    宿主
    • 21
    • 12
    • 9
    • 4
    • 3
    • 1
    小鼠
    资源
    • 31
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 < 0.1 ng/mL, measured by a cell proliferation assay using BALB/c 3T3 cells, corresponding to a specific activity of > 1.0x 10^7 units/mg.
    AA 977-1029, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE and HPLC analysis.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product EGF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant mouse Epidermal Growth Factor (rmEGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmEGF should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    EGF (Epidermal Growth Factor (EGF))
    Abstract
    EGF 产品
    别名
    HOMG4 Protein, URG Protein, AI790464 Protein, CEGF Protein, epidermal growth factor Protein, pro-epidermal growth factor Protein, EGF Protein, egf Protein, CpipJ_CPIJ020278 Protein, Egf Protein
    背景
    Epidermal Growth Factor (EGF) was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).Recombinant mouse Epidermal Growth Factor (rmEGF) produced in E. coli is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rmEGF is obtained by proprietary chromatographic techniques with a molecular mass of 6.2 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Epidermal Growth Factor, Urogastrone, URG
    分子量
    6.2 kDa, observed by reducing SDS-PAGE.
    UniProt
    P01132
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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