CNTF Protein (AA 1-200)
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- 抗原 See all CNTF 蛋白
- CNTF (Ciliary Neurotrophic Factor (CNTF))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-200
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宿主
- 人
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资源
- HEK-293T Cells
- 产品特性
- ED50 < 0.20 μg/mL, measured in a cell proliferation assay using TF-1 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Ciliary Neurotrophic Factor (CNTF) (AA 1-200) protein (His tag)
CNTF 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ciliary Neurotrophic Factor (CNTF) (AA 1-200) protein (His tag)CNTF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ciliary Neurotrophic Factor (CNTF) (AA 1-200) protein (GST tag)CNTF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ciliary Neurotrophic Factor (CNTF) proteinCNTF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Ciliary Neurotrophic Factor (CNTF) (AA 4-196), (partial) protein (His tag)CNTF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Human Ciliary Neurotrophic Factor (CNTF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Ciliary Neurotrophic Factor (CNTF) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- CNTF (Ciliary Neurotrophic Factor (CNTF))
- Abstract
- CNTF 产品
- 别名
- GPA Protein, CNTF Protein, HCNTF Protein, AI429687 Protein, ciliary neurotrophic factor Protein, CNTF Protein, Cntf Protein
- 背景
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Ciliary neurotrophic factor (CNTF) is a polypeptide initially purified from chick embryo ocular tissue and identified as a trophic factor for embryonic chick ciliary parasympathetic neurons in culture. Subsequent studies have demonstrated that CNTF is a survival factor for additional neuronal cell types including: dorsal root ganglion sensory neurons, sympathetic ganglion neurons, embryonic motor neurons, major pelvic ganglion neurons and hippocampal neurons. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. The gene for human CNTF has been localized to the proximal region of the long arm of chromosome 11. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL-6, IL-11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal-transducing subunit in their receptor complexes.
Synonyms: Ciliary Neurotrophic Factor - 分子量
- 22-28 kDa, observed by reducing SDS-PAGE.
- UniProt
- P26441
- 途径
- JAK/STAT Signaling
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