Cardiotrophin 1 Protein (CTF1) (AA 2-203)
CTF1
宿主: 小鼠
宿主: HEK-293T Cells
Recombinant
> 95 % as analyzed by SDS-PAGE.
Active
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- 抗原 See all Cardiotrophin 1 (CTF1) 蛋白
- Cardiotrophin 1 (CTF1)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 2-203
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宿主
- 小鼠
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资源
- HEK-293T Cells
- 产品特性
- The EC50 value of Mouse Cardiotrophin-1 determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.25 ng/mL, corresponding to a specific activity of ≥ 0.8 x 10^6 units/mg.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product CTF1 蛋白
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Cardiotrophin 1 (CTF1) (Active) protein
CTF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Cardiotrophin 1 (CTF1) (AA 1-201) protein (GST tag)CTF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Mouse Cardiotrophin-1 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Mouse Cardiotrophin-1 should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- Cardiotrophin 1 (CTF1)
- 别名
- Cardiotrophin-1(CT-1) (CTF1 产品)
- 别名
- CTF1 Protein, ct1 Protein, ct-1 Protein, ctf2 Protein, CT-1 Protein, CT1 Protein, cardiotrophin 1 Protein, cardiotrophin-1 Protein, CTF1 Protein, ctf1 Protein, Ctf1 Protein, LOC100736818 Protein
- 背景
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Cardiotrophin-1 (CT-1) is a member of the cytokine family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). CT-1 is associated with the pathophysiology of several types of heart disease including hypertension, myocardial infarction, valvular heart disease, and congestive heart failure. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-kappaB DNA -binding activities. CT-1 is highly expressed in the heart, skeletal muscle, prostate and ovary and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine.Recombinant mouse Cardiotrophin-1 produced in HEK293 cells is a polypeptide chain containing 202 amino acids. A fully biologically active molecule, rmCT-1 has a molecular mass of 22-27 kDa analyzed by reducing SDS-PAGE.
Synonyms: CTF1, CT-1 - 分子量
- 22-27 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q60753
- 途径
- JAK/STAT Signaling
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