Betacellulin Protein (BTC) (AA 32-111)
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- 抗原 See all Betacellulin (BTC) 蛋白
- Betacellulin (BTC)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 32-111
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宿主
- 小鼠
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资源
- HEK-293T Cells
- 产品特性
- ED50 <0.08 ng/mL, measured in a cell proliferation assay using 3T3 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product BTC 蛋白
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 70-178) protein (GST tag)BTC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-118) protein (His tag)BTC 宿主: 人 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant murine Betacellulin remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Murine Betacellulin should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- 有效期
- 6 months
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- 抗原
- Betacellulin (BTC)
- 别名
- Betacellulin (BTC 产品)
- 别名
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- 背景
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Betacellulin, also known as BTC, belongs to the EGF family of growth factors. It is expressed in many tissues, such as kidney, pancreas and small intestine. Betacellulin is initially synthesized as a membrane-bound precursor containing multiple EGF-like domains in its extracellular region, and is released from the membrane by proteolytic cleavage. BTC is the ligand for EGFR/ErbB receptor tyrosine kinases, and plays a role in cell growth and differentiation. BTC has been reported to promote beta cell growth and differentiation in the pancreas. Pancreas-specific expression of this gene may induce islet neogenesis and remediate hyperglycemia in type I diabetes.
Synonyms: BTC - 分子量
- 19-24 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q543J8
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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