Defensin beta 3 Protein (DEFB3)
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- 抗原 See all Defensin beta 3 (DEFB3) 蛋白
- Defensin beta 3 (DEFB3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 序列
- KKVYNAVSCM TNGGICWLKC SGTFREIGSC GTRQLKCCKK K
- 产品特性
- Fully biologically active when compared to standard. Measured by its antimicrobial activity against E. coli. The ED50 for this effect is typically 4-20 μg/mL.
- 纯度
- > 95 % by SDS-PAGE and HPLC analyses.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- < 1 EU/μg of rRtBD-3 as determined by LAL method.
- Top Product
- Discover our top product DEFB3 蛋白
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Defensin beta 3 (DEFB3) (Active) protein
DEFB3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Defensin beta 3 (DEFB3) (AA 23-67) protein (His tag)DEFB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Defensin beta 3 (DEFB3) (AA 23-63) protein (His tag)DEFB3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 缓冲液
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- 抗原
- Defensin beta 3 (DEFB3)
- 别名
- beta-Defensin 3 (BD-3) (DEFB3 产品)
- 别名
- BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, BNBD-3 Protein, BNBD-6 Protein, BNDB-3 Protein, BNDB-6 Protein, BNDB3 Protein, DEFB103A Protein, DEFB2 Protein, DEFB6 Protein, bnbd3 Protein, defb405 Protein, defensin beta 103A Protein, defensin beta 3 Protein, beta-defensin 3 Protein, DEFB103A Protein, Defb3 Protein, DEFB3 Protein
- 背景
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Beta defensin-3, also known as BD-3 and DEFB-3, is a membrane active cationic peptide that functions in inflammation and innate immune responses and coded by Defb 3 gene on chromosome 8 in mouse. There are at least 30 b-defensins which are distinguished from beta-defensins by the connectivity pattern of their three intramolecular disulfide bonds. BD3 is widely expressed among epithelial tissues, notably by keratinocytes and airway epithelial cells. It is upregulated in response to proinflammatory cytokines, microbial and viral infections, and at the edges of skin wounds. BD3 induction in osteoarthritis chondrocytes promotes MMP1 and 13 productions and inhibits TIMP1 and 2 expressions.
Synonyms: Beta-defensin 3, BD-3, Defensin beta 3, Defb3 - 分子量
- 4.5 kDa, a single non-glycosylated polypeptide chain containing 41 amino acids.
- 途径
- Production of Molecular Mediator of Immune Response
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