Amphiregulin Protein (AREG) (AA 101-198)
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- 抗原 See all Amphiregulin (AREG) 蛋白
- Amphiregulin (AREG)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 101-198
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宿主
- 人
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资源
- HEK-293T Cells
- 产品特性
- ED50 < 0.2 ng/mL, measured in a cell proliferation assay using 3T3 cells.
- 纯度
- > 95 % as analyzed by SDS-PAGE.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product AREG 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Human Amphiregulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Amphiregulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- Amphiregulin (AREG)
- 别名
- Amphiregulin (AREG 产品)
- 别名
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- 背景
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Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-alpha, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-alpha receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF) - 分子量
- 15-20 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q5U026
- 途径
- RTK signaling, EGFR Signaling Pathway
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