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Amphiregulin Protein (AREG) (AA 101-198)

AREG 宿主: 人 宿主: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2017667
发货至: 中国
  • 抗原 See all Amphiregulin (AREG) 蛋白
    Amphiregulin (AREG)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 101-198
    宿主
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    资源
    • 17
    • 3
    • 2
    HEK-293T Cells
    产品特性
    ED50 < 0.2 ng/mL, measured in a cell proliferation assay using 3T3 cells.
    纯度
    > 95 % as analyzed by SDS-PAGE.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product AREG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against PBS.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant Human Amphiregulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Amphiregulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    有效期
    6 months
  • 抗原
    Amphiregulin (AREG)
    别名
    Amphiregulin (AREG 产品)
    别名
    AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
    背景
    Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-alpha, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-alpha receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
    Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF)
    分子量
    15-20 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q5U026
    途径
    RTK signaling, EGFR Signaling Pathway
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