MAD6 Protein, MXD6 Protein, ROX Protein, bHLHd3 Protein, etID309773.22 Protein, fb16b12 Protein, fb55f03 Protein, wu:fb16b12 Protein, wu:fb55f03 Protein, wu:fd06a08 Protein, wu:fz74f10 Protein, Rox Protein, Mnt Protein, zgc:165490 Protein, mnt Protein, rox Protein, MGC98824 Protein, MAX network transcriptional repressor Protein, max interactor 1, dimerization protein Protein, max binding protein Protein, MAX network transcriptional repressor b Protein, MAX network transcriptional repressor L homeolog Protein, MNT Protein, mxi1 Protein, Mnt Protein, mntb Protein, mnt.L Protein
背景
Synonyms: MAD6,MXD6,ROX,bHLHd3 Gene Description: MAX binding protein Gene Name: MNT Gene Summary: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. GenBank: AK291596.1, BAF84285.1