Recombinant Human Tumor necrosis factor receptor superfamily member 13B/TNFRSF13B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-His166) of Human TNFRSF13B fused with a polyhistidine tag and FC tag at the C-terminus.
纯度
> 95 % as determined by reducing SDS-PAGE.
过滤
0.2 μm filtered
内毒素水平
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
TNFRSF13B
宿主: 小鼠
宿主: Tobacco (Nicotiana tabacum)
Recombinant
≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
限制
仅限研究用
状态
Lyophilized
溶解方式
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
缓冲液
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
注意事项
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
储存条件
4 °C/-20 °C/-80 °C
储存方法
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
有效期
3 months
抗原
TACI (TNFRSF13B)
(Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), is also known as Transmembrane activator and CAML interactorand, CD267 and TACI. TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TNFRSF13B is highly expressed in spleen, small intestine, thymus and peripheral blood leukocytes. TNFRSF13B mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. TNFRSF13B is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. Defects in TNFRSF13B are the cause of immunodeficiency common variable type 2 (CVID2) and cause of immunoglobulin A deficiency 2 (IGAD2). Alternative Names: Tumor necrosis factor receptor superfamily member 13B, TNFRSF13B, Transmembrane activator, CAML interactorand, CD267,TACI.