PRSS2 蛋白
PRSS2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 96 % by SDS-PAGE
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- 抗原 See all PRSS2 蛋白
- PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 纯度
- > 96 % by SDS-PAGE
- Top Product
- Discover our top product PRSS2 蛋白
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Protease, serine, 2 (Trypsin 2) (PRSS2) (AA 1-247) protein (GST tag)
PRSS2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AP, AA, WB
Protease, serine, 2 (Trypsin 2) (PRSS2) (Active) protein (His tag)PRSS2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Tris-HCl (pH 7.4 +/- 0.2) with 0.02 % NaN3.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 储存条件
- 4 °C
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- 抗原
- PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
- 别名
- Trypsinogen 2 (PRSS2 产品)
- 背景
- Trypsinogen is the precursor form or zymogen of the pancreatic enzyme trypsin. It functions as storage of an inactive form of trypsin so that it may be kept in pancreas and released in significant amount when required for protein digestion. Rowen et al. (1996) found that only 2 of 3 pancreatically expressed trypsinogen cDNAs correspond to trypsinogen genes in the TCRB locus, T4 was denoted trypsinogen 1 and T8 was denoted trypsinogen 2. The third pancreatic cDNA, identified independently as trypsinogen 3 and 4, is distinct from the third apparently functional trypsinogen gene (T6) in the TCRB locus but related to the other pancreatic trypsinogens. Teich et al. (2004) demonstrated that the E79K mutation in PRSS1 activated anionic trypsinogen 2-fold better than wildtype cationic trypsin did, whereas the common pancreatitis-associated mutants R122H and N29I had no such effect. The observations not only suggested a novel mechanism of action for pancreatitis-associated trypsinogen mutations, but also highlighted the importance of interactions between the 2 major trypsinogen isoforms in the development of genetically determined chronic pancreatitis.
- 分子量
- 31 kDa
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