NGFB 蛋白
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- 抗原 See all NGFB 蛋白
- NGFB (Nerve Growth Factor beta (NGFB))
- 蛋白类型
- Native
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 小鼠
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NGFB 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with sterile 18 mΩ/cm^3 H2O.
- 缓冲液
- 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)
- 储存液
- Without preservative
- 储存条件
- 4 °C
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- 抗原
- NGFB (Nerve Growth Factor beta (NGFB))
- 别名
- NGF beta (NGFB 产品)
- 背景
- Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.
- 分子量
- 26.5 kDa
- 途径
- NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
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