宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
SDS, ELISA, HPLC
Active
限制
仅限研究用
状态
Liquid
缓冲液
10mM PBS (pH 7.5)
储存液
Without preservative
储存条件
4 °C
抗原
C-Peptide
背景
Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.