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C-Peptide 蛋白

This Recombinant C-Peptide protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1880359
发货至: 中国

Quick Overview for C-Peptide 蛋白 (ABIN1880359)

抗原

See all C-Peptide 蛋白
C-Peptide

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by HPLC & SDS-PAGE
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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10mM PBS (pH 7.5)

    储存液

    Without preservative

    储存条件

    4 °C
  • 抗原

    C-Peptide

    背景

    Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.
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