Survivin Protein (AA 1-142)
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- 抗原 See all Survivin (BIRC5) 蛋白
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-142
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Baculoviral IAP Repeat-Containing Protein 5/BIRC5/Survivin
- 序列
- MGAPTLPPAW QPFLKDHRIS TFKNWPFLEG CACTPERMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLGE FLKLDRERAK NKIAKETNNK KKEFEETAKK VRRAIEQLAA MD
- 产品特性
- Recombinant Human Baculoviral IAP Repeat-Containing Protein 5/BIRC5 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp142) of Human BIRC5.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product BIRC5 蛋白
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Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (His tag)
custom-made BIRC5 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-140) protein (His tag)custom-made BIRC5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (Calmodulin (CaM))BIRC5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Baculoviral IAP Repeat-Containing 5 (BIRC5) (AA 1-142) protein (GST tag)BIRC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 别名
- BIRC5 (BIRC5 产品)
- 背景
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Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
Alternative Names: Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4 - 分子量
- 20.4 kDa
- UniProt
- O15392
- 途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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