GDNF Protein (AA 20-211) (Fc Tag,His tag)
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- 抗原 See all GDNF 蛋白
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-211
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宿主
- 人
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资源
- 人细胞
- 标记
- This GDNF protein is labelled with Fc Tag,His tag.
- 原理
- Recombinant Human Glial Cell Line-Derived Neurotrophic Factor/GDNF (C-Fc-6His)
- 序列
- FPLPAGKRPP EAPAEDRSLG RRRAPFALSS DSNMPEDYPD QFDDVMDFIQ ATIKRLKRSP DKQMAVLPRR ERNRQAAAAN PENSRGKGRR GQRGKNRGCV LTAIHLNVTD LGLGYETKEE LIFRYCSGSC DAAETTYDKI LKNLSRNRRL VSDKVGQACC RPIAFDDDLS FLDDNLVYHI LRKHSAKRCG CIVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH
- 产品特性
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Recombinant Human Glial Cell Line-Derived Neurotrophic Factor/GDNF (C-Fc-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GDNF 蛋白
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Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein
GDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein (His tag)GDNF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-177) protein (GST tag)GDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 1-211) protein (GST tag)GDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) protein (Fc Tag)GDNF 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
- 别名
- GDNF (GDNF 产品)
- 别名
- gdnf Protein, GDNF Protein, AI385739 Protein, gdnfa Protein, hfb1-gdnf Protein, ATF1 Protein, ATF2 Protein, HFB1-GDNF Protein, HSCR3 Protein, glial cell derived neurotrophic factor Protein, glial cell derived neurotrophic factor a Protein, glial cell line derived neurotrophic factor Protein, glial cell derived neurotrophic factor L homeolog Protein, Gdnf Protein, gdnfa Protein, GDNF Protein, gdnf.L Protein
- 背景
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Recombinant Human Glial cell line-derived neurotrophic factor/GDNF/ATF is produced by our mammalian expression system. The target protein is expressed with sequence (Phe20-Ile211) of Human GDNF fused with FC and polyhistidine tag at the C-terminus.
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 AA residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 AA residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease. - 分子量
- 49.6 kDa
- UniProt
- P39905
- 途径
- RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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