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Leptin Receptor Protein (LEPR) (C-Term, Extracellular Domain)

LEPR 宿主: 人 宿主: HEK-293T Cells Recombinant > 98 %, as determined by SDS-PAGE and HPLC Active
产品编号 ABIN1684639
发货至: 中国
  • 抗原 See all Leptin Receptor (LEPR) 蛋白
    Leptin Receptor (LEPR)
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    C-Term, Extracellular Domain
    宿主
    • 13
    • 4
    • 2
    • 1
    资源
    • 6
    • 6
    • 5
    • 2
    HEK-293T Cells
    特异性
    Optimized DNA sequence encoding extracellular domain of human leptin receptor including a C-terminal Human IgG1 Fc tag was expressed in HEK293 cells.
    产品特性
    Recombinant human leptin receptor is a homodimer protein consisting of two 1070 amino acid residue subunit chains, due to glycosylation migrates as an approximately 160kDa protein on SDS-PAGE.
    纯度
    > 98 %, as determined by SDS-PAGE and HPLC
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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    Discover our top product LEPR 蛋白
  • 说明

    Biologically active: Measured by its ability to bind immobilized recombinant human Leptin (1 µg/mL) at a linear concentration range of 0.01-4 µg/mL.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS solution, pH7.2
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    The lyophilized antibody is stable for at least 1 year from date of receipt at -20 °C. Upon reconstitution, this antibody can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months without detectable loss of activity.
    有效期
    12 months
  • 抗原
    Leptin Receptor (LEPR)
    别名
    LEPR (LEPR 产品)
    别名
    CD295 Protein, LEP-R Protein, LEPRD Protein, OB-R Protein, OBR Protein, obr Protein, cd295 Protein, ob-rb Protein, Fa Protein, LEPROT Protein, Leprb Protein, Modb1 Protein, OB-RGRP Protein, Obr Protein, db Protein, diabetes Protein, obese-like Protein, obl Protein, ObRb Protein, Ob-R Protein, Ob-RM Protein, lepr Protein, leptin receptor Protein, leptin receptor S homeolog Protein, LEPR Protein, lepr Protein, Lepr Protein, lepr.S Protein
    背景
    FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs, FGF10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. Human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells. Recombinant FGF-10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre-adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired.
    UniProt
    P48357
    途径
    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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