Optimized DNA sequence encoding extracellular domain of human IL-17RC receptor including a C terminal Human IgG1 Fc tag was expressed in HEK293 cells.
产品特性
Recombinant IL17RC-Fc is a homodimer protein consisting of 675 amino acid residue subunits, due to glycosylation migrates as an approximately 100kD protein under reducing SDS-PAGE conditions.
纯度
> 98 %, as determined by SDS-PAGE and HPLC
过滤
0.2 μm filtered
内毒素水平
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
IL17RC
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
限制
仅限研究用
状态
Lyophilized
缓冲液
PBS solution, pH7.2
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
Common gamma chain Interleukin (IL)-2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common gamma chain (gamma c). Despite some redundancy, thesecytokines that signal through the gamma c (gamma c cytokines) have essentially distinct and oftencritical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated,directly or indirectly, in T-cell leukemogenesis.