PDGF-AA Homodimer (Homodimer) (Active) 蛋白
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % by SDS-PAGE
Active
-
- 抗原
- PDGF-AA Homodimer
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- Homodimer
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 原理
- PDGF-AA
- 序列
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- 特异性
- Chromosomal location:7p22
- 产品特性
- Length (aa):125
- 纯度
- > 95 % by SDS-PAGE
- 内毒素水平
- < 0.1 ng per ug of PDGF-AA
-
PDGF-AA Homodimer (AA 87-196) protein (His tag)
宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
PDGF-AA Homodimer protein宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
-
- 应用备注
- The biological activity was determined by the induction of proliferation in NHDF cells (Normal Human Dermal Fibroblasts).
- 说明
-
Cytokines & Growth Factors
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. The lyophilized PDGF-AA should be reconstituted in water to a concentration not lower than 50 μg/mL. For long term storage we recommend to add at least 0.1 % human or bovine serum albumin.
- 缓冲液
- 50 mM acetic acid
- 注意事项
- Centrifuge vial prior to opening. Avoid repeated freeze-thaw cycles.
- 储存条件
- RT,-20 °C,-80 °C
- 储存方法
- The lyophilized PDGF-AA is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted PDGF-AA is best stored at -20°C to -70°C. Avoid repeated freeze-thaw cycles.
-
- 抗原
- PDGF-AA Homodimer
- 别名
- PDGF-AA
- 别名
- PDGF-A Protein, PDGF1 Protein, AA409063 Protein, CD142 Protein, Cf-3 Protein, Cf3 Protein, TF Protein, PDGFACP Protein, platelet derived growth factor subunit A Protein, coagulation factor III Protein, platelet derived growth factor, alpha Protein, PDGFA Protein, F3 Protein, Pdgfa Protein
- 背景
-
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two A chains (250 total amino acids).
Synonyms: PDGFA, PDGF1, PDGF-A - 分子量
- 28.5 kDa
- 基因ID
- 5154
- NCBI登录号
- NM_002607, NP_002598
- UniProt
- P04085
-
You are here:
