Annexin V Protein (GST tag)
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- 抗原 See all Annexin V (ANXA5) 蛋白
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Annexin V protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to phosphatidylserine (PS).
- 交叉反应
- 人
- 产品特性
- Recombinant human annexin V fused to a GST-tag.
- 纯度
- >95 % (SDS-PAGE)
- Top Product
- Discover our top product ANXA5 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. In PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C. - 有效期
- 12 months
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Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).
: "
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Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).
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- 抗原
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- 别名
- Annexin V (ANXA5 产品)
- 背景
- Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
- 分子量
- ~52kDa (SDS-PAGE)
- UniProt
- P08758
- 途径
- Apoptosis
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