IL-37 Protein (His tag)
-
- 抗原 See all IL-37 (IL37) 蛋白
- IL-37 (IL37) (Interleukin 37 (IL37))
- 蛋白类型
- Recombinant
- 宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This IL-37 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 原理
- IL-37 (aa 46-218) (human) (rec.) (His)
- 交叉反应
- 人
- 产品特性
- Human IL-37 (aa Val46-Asp218) is fused at the C-terminus to a His-tag.
- 纯度
- >95 % (SDS-PAGE)
- 过滤
- Sterile filtered
- 内毒素水平
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product IL37 蛋白
-
Interleukin 37 (IL37) (AA 1-218) protein (GST tag)
IL37 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 37 (IL37) (Active) proteinIL37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 37 (IL37) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)IL37 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute in distilled water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
- 注意事项
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- 有效期
- 6 months
-
- 抗原
- IL-37 (IL37) (Interleukin 37 (IL37))
- 别名
- IL-37 (IL37 产品)
- 背景
-
Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1
IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
- 分子量
- ~20kDa (SDS-PAGE)
- UniProt
- Q9NZH6
-
