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Calreticulin Protein (CALR) (His tag)
CALR
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
>90 % (SDS-PAGE)
SDS
产品细节
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See all Calreticulin (CALR) 蛋白
Calreticulin (CALR)
蛋白类型
Recombinant
宿主
All origins for Calreticulin 蛋白
人
资源
All sources for Calreticulin 蛋白
大肠杆菌(E. Coli)
标记
This Calreticulin protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
交叉反应
人
产品特性
Human calreticulin (aa18-417) is fused at the C-terminus to a His-tag.
纯度
>90 % (SDS-PAGE)
过滤
0.2 μm filtered
内毒素水平
<1EU/μg purified protein (LAL test, Lonza).
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
Lot specific
缓冲液
0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C.
有效期
3 months
目标详细情况
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Calreticulin (CALR)
别名
Calreticulin (CALR 产品 )
别名
CRT Protein, RO Protein, SSA Protein, cC1qR Protein, crc Protein, crt Protein, Calregulin Protein, CG9429 Protein, Clr Protein, Dmel\\CG9429 Protein, anon-EST:Liang-2.11 Protein, anon-EST:Liang-2.17 Protein, anon-EST:fe3D7 Protein, clone 2.11 Protein, clone 2.17 Protein, eth Protein, potp Protein, cc1qr Protein, ssa Protein, NV19007 Protein, CRP55 Protein, ERp60 Protein, HACBP Protein, CHOT1 Protein, CHT1 Protein, CT1 Protein, AA589632 Protein, CRTR Protein, Creat Protein, CCDS1 Protein, calrl2 Protein, fc66d10 Protein, wu:fc66d10 Protein, wu:fj50c03 Protein, zgc:66153 Protein, calreticulin Protein, calreticulin L homeolog Protein, Calreticulin Protein, putative calreticulin Protein, solute carrier family 6 member 8 Protein, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Protein, CALR Protein, calr.L Protein, Crt Protein, crt Protein, CRT Protein, Calr Protein, calr Protein, LMJF_31_2600 Protein, Crc Protein, Slc6a8 Protein, SLC6A8 Protein, LOC8269812 Protein
背景
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the 'calreticulin/calnexin cycle' that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
分子量
~55kDa (SDS-PAGE)
UniProt
P27797
途径
Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Nuclear Hormone Receptor Binding , ER-Nucleus Signaling , Unfolded Protein Response
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