GPR177/WLS Protein (AA 101-232) (His tag)
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Quick Overview for GPR177/WLS Protein (AA 101-232) (His tag) (ABIN1098794)
抗原
See all GPR177/WLS (WLS) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 101-232
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标记
- This GPR177/WLS protein is labelled with His tag.
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序列
- MGSSHHHHHH SSGLVPRGSH MGSMEMSPWF QFMLFILQLD IAFKLNNQIR ENAEVSMDVS LAYRDDAFAE WTEMAHERVP RKLKCTFTSP KTPEHEGRYY ECDVLPFMEI GSVAHKFYLL NIRLPVNEKK KINVGIGEIK DIRLVGIHQN GGFTK
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纯化方法
- > 90% by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- GPR177/WLS (WLS) (Wntless Homolog (WLS))
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别名
- GPR177/WLS
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背景
- WLS, a Wnt trafficking regulator, is a multipass transmembrane protein that regulates the sorting and secretion of Wnt protein. It is required for organogenesis during embryogenesis and for the establishment of the anterior-posterior axis. WLS promotes various cancers such as glioma tumourigenesis. The gene encoding WLS maps to human chromosome 1 and is expressed as multiple alternatively spliced isoforms. Recombinant human WLS protein, fused to His-tag at N-terminus, was expressed in E. coli.
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分子量
- 17.8 kDa (155aa)
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NCBI登录号
- NP_079187
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途径
- WNT signaling
抗原
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