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HFE Protein (His tag)

HFE 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN1098722
发货至: 中国
  • 抗原 See all HFE 蛋白
    HFE (Hemochromatosis (HFE))
    蛋白类型
    Recombinant
    宿主
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    资源
    • 5
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    大肠杆菌(E. Coli)
    标记
    This HFE protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 85 % by SDS - PAGE
  • 说明

    Synonyms: Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    HFE (Hemochromatosis (HFE))
    别名
    HFE (HFE 产品)
    别名
    HFE1 Protein, HH Protein, HLA-H Protein, MVCD7 Protein, TFQTL2 Protein, MR2 Protein, hemochromatosis Protein, HFE Protein, Hfe Protein
    背景
    HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    35.7kDa (308aa)
    NCBI登录号
    NP_000401
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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