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- 抗原 See all TDG 蛋白
- TDG (Thymine-DNA Glycosylase (TDG))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TDG protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯度
- > 90 % by SDS - PAGE
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Thymine-DNA Glycosylase (TDG) (AA 312-409) protein (GST tag)
TDG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Thymine-DNA Glycosylase (TDG) (AA 1-410) protein (GST tag)TDG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Synonyms: Thymine-DNA glycosylase, G/T mismatch-specific thymine DNA glycosylase
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 Urea, 10% glycerol, 0.1 M NaCl
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- TDG (Thymine-DNA Glycosylase (TDG))
- 别名
- TDG (TDG 产品)
- 别名
- 5-MCDG Protein, wu:fb44b11 Protein, zgc:110622 Protein, MGC82456 Protein, MGC89441 Protein, E130317C12Rik Protein, JZA-3 Protein, Jza1 Protein, hTDG Protein, thymine DNA glycosylase Protein, thymine DNA glycosylase, tandem duplicate 1 Protein, putative g/t mismatch-specific thymine DNA glycosylase Protein, G/T mismatch-specific thymine DNA glycosylase Protein, thymine DNA glycosylase S homeolog Protein, thymine-DNA glycosylase Protein, TDG Protein, tdg.1 Protein, Smp_149220 Protein, Tsp_05734 Protein, tdg.S Protein, tdg Protein, Tdg Protein
- 背景
- Thymine-DNA glycosylase, also known as TDG, belongs to the TDG/mug DNA glycosylase family. TDG is a nuclear protein which corrects G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. Recombinant human TDG protein, fused to His-tag at N-terminus, was expressed in E.coli
- 分子量
- 48.4 kDa (433aa)
- 途径
- DNA Damage Repair, Chromatin Binding
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