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MVK Protein (His tag)

MVK 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098525
发货至: 中国
  • 抗原 See all MVK 蛋白
    MVK (Mevalonate Kinase (MVK))
    蛋白类型
    Recombinant
    宿主
    • 7
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    • 1
    • 1
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    资源
    • 7
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    • 1
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    大肠杆菌(E. Coli)
    标记
    This MVK protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
  • 说明

    Synonyms: Mevalonate kinase, LRBP, MK, MVLK

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    MVK (Mevalonate Kinase (MVK))
    别名
    MVK (MVK 产品)
    别名
    F21A20.160 Protein, F21A20_160 Protein, MEVALONATE KINASE Protein, MVK Protein, mevalonate kinase Protein, DDBDRAFT_0168621 Protein, DDBDRAFT_0302479 Protein, DDB_0168621 Protein, DDB_0302479 Protein, LRBP Protein, MK Protein, MVLK Protein, POROK3 Protein, 2310010A05Rik Protein, AI256848 Protein, AI414037 Protein, zgc:103473 Protein, mevalonate kinase Protein, mvk Protein, hypothetical protein Protein, MVK Protein, MK Protein, MA_RS03165 Protein, PAB_RS02890 Protein, LMOf2365_0011 Protein, mvk Protein, RCI_RS14145 Protein, TGAM_RS08735 Protein, MMAH_RS07705 Protein, TAGG_RS01605 Protein, SHELL_RS02965 Protein, MVOL_RS03085 Protein, Igag_1464 Protein, VDIS_RS11260 Protein, MFER_RS04560 Protein, DESMU_RS01555 Protein, ARCVE_RS02955 Protein, MZHIL_RS05110 Protein, Mvk Protein
    背景
    Mevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive,hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Recombinant human MVK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    44.8 kDa (419aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_001107657
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