14-3-3 sigma/SFN Protein (AA 1-248)
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- 抗原 See all 14-3-3 sigma/SFN (SFN) 蛋白
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-248
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Stratifin/SFN
- 序列
- MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
- 产品特性
- Recombinant Human Stratifin is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ser248) of Human Stratifin.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SFN 蛋白
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Stratifin (SFN) (AA 3-238) protein (GST tag)
SFN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Stratifin (SFN) (AA 1-248) protein (GST tag)SFN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Stratifin (SFN) (AA 1-248), (full length) protein (GST tag)SFN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Stratifin (SFN) proteinSFN 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Stratifin (SFN) protein (Myc-DYKDDDDK Tag)SFN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, 1 mM EDTA, 1 mM DTT, pH 7.4.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 别名
- Stratifin (SFN 产品)
- 别名
- YWHAS Protein, Er Protein, Mme1 Protein, Ywhas Protein, stratifin Protein, SFN Protein, Sfn Protein
- 背景
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Stratifin (SFN) belongs to the 14-3-3 family of proteins that act as important regulators of intracelluar signal transduction through their ability to bind specific motifs phosphorylated on serine or threonine. There are at least seven isoforms that have been identified in mammals (beta, gamma, epsilon, sigma, zeta, tau and eta). SFN can detected in many tissues, highly expressed in stratified squamous keratinizing epithelium. SFN is indicated as an epithelial cell marker and serves as a tumor suppressor whose expression can be down regulated by methylation. In addition, SFN plays a key role in maintaining the G2 checkpoint in cells and preventing mitotic death.
Alternative Names: 14-3-3 Protein Sigma, Epithelial Cell Marker Protein 1, Stratifin, SFN, HME1 - 分子量
- 27.77 kDa
- UniProt
- P31947
- 途径
- p53 Pathway, Myometrial Relaxation and Contraction
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