PCBD1 Protein (AA 2-104) (His tag)
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- 抗原 See all PCBD1 蛋白
- PCBD1 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-104
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PCBD1 protein is labelled with His tag.
- 原理
- Recombinant Human Pterin-4-α-Carbinolamine Dehydratase/PHS/PCBD1 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT
- 产品特性
- Recombinant Human Pterin-4-alpha-Carbinolamine Dehydratase/PCBD1 is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Thr104) of Human PCBD1 fused with a His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PCBD1 蛋白
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Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) (AA 1-104) protein (His tag)
PCBD1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) (AA 1-104) protein (GST tag)PCBD1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) (AA 2-104) protein (His tag)PCBD1 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) protein (Myc-DYKDDDDK Tag)PCBD1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, pH 8.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- PCBD1 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1))
- 别名
- PHS/PCBD1 (PCBD1 产品)
- 别名
- BcDNA:LP07248 Protein, CG1963 Protein, Dmel\\CG1963 Protein, PCD Protein, pcbd Protein, zgc:73389 Protein, Xdcoh Protein, dcoh Protein, pcd Protein, phs Protein, DDBDRAFT_0204977 Protein, DDBDRAFT_0305045 Protein, DDB_0204977 Protein, DDB_0305045 Protein, Dcoh Protein, Pcbd Protein, DCOH Protein, PHS Protein, PCBD Protein, DCoH Protein, TCF1 Protein, pterin-4a-carbinolamine dehydratase Protein, pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha Protein, pterin-4-alpha-carbinolamine dehydratase Protein, pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 Protein, pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha L homeolog Protein, pterin-4 alpha-carbinolamine dehydratase 1 Protein, Pcd Protein, pcbd1 Protein, Tb11.02.4890 Protein, pcbd Protein, Fbal_2579 Protein, Ftrac_2004 Protein, Celal_2911 Protein, Isop_1133 Protein, Celly_0291 Protein, Pcbd1 Protein, pcbd1.L Protein, PCBD1 Protein
- Sub Type
- Fusionprotein
- 背景
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Pterin-4-alpha-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-alpha-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D). HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
Alternative Names: Pterin-4-Alpha-Carbinolamine Dehydratase, PHS, 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha, DCoH, Dimerization Cofactor of HNF1, Phenylalanine Hydroxylase-Stimulating Protein, Pterin Carbinolami - 分子量
- 14.2 kDa
- UniProt
- P61457
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