NCR3 Protein (AA 19-138) (His tag)
-
- 抗原 See all NCR3 蛋白
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-138
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This NCR3 protein is labelled with His tag.
- 原理
- Recombinant Human NCR3/NKp30/CD337 (C-6His)
- 序列
- LWVSQPPEIR TLEGSSAFLP CSFNASQGRL AIGSVTWFRD EVVPGKEVRN GTPEFRGRLA PLASSRFLHD HQAELHIRDV RGHDASIYVC RVEVLGLGVG TGNGTRLVVE KEHPQLGAGT VDHHHHHH
- 产品特性
-
Recombinant Human NCR3/NKp30/CD337 (C-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product NCR3 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
- 别名
- Natural Cytotoxicity Triggering Receptor 3/NCR3 (NCR3 产品)
- 别名
- MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
- 背景
-
Recombinant Human Natural Cytotoxicity Triggering Receptor 3/NCR3 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu19-Thr138) of Human NCR3.
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed 'Natural Cytotoxicity Receptors'. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity. - 分子量
- 12.84 kDa
- UniProt
- O14931
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-