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IGF1 Protein (AA 52-118)

IGF1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096867
发货至: 中国
  • 抗原 See all IGF1 蛋白
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    蛋白类型
    Recombinant
    产品特性
    AA 52-118
    宿主
    • 24
    • 13
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 42
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Insulin-Like Growth Factor I/IGF-I/IGF1 (4-70)
    序列
    TLCGAELVDA LQFVCGDRGF YFNKPTGYGS SSRRAPQTGI VDECCFRSCD LRRLEMYCAP LKPAKSA
    产品特性
    Recombinant Human Insulin-like Growth Factor I/IGF is produced with our E. coli expression system. The target protein is expressed with sequence (T52-A118) of Human IGF1.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.05 ng/μg (0.5 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IGF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in 500 mM Acetic Acid.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 300 mM NaAc, pH 6.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    别名
    igf-i (IGF1 产品)
    别名
    IGF-I Protein, IGF1A Protein, IGFI Protein, C730016P09Rik Protein, Igf-1 Protein, Igf-I Protein, Npt2B Protein, IGF-1 Protein, IGFIA Protein, IGF-IB Protein, igf1 Protein, IGF-1L Protein, IGF-1a Protein, IGF1 Protein, igf-1 Protein, igf1-A Protein, igf1.S Protein, xigf1 Protein, insulin like growth factor 1 Protein, insulin-like growth factor 1 Protein, insulin-like growth factor I Protein, insulin like growth factor 1 L homeolog Protein, IGF1 Protein, Igf1 Protein, LOC100136741 Protein, igf1 Protein, LOC678666 Protein, igf1.L Protein, LOC104911603 Protein
    背景
    Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
    Alternative Names: Insulin-Like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IGF1, IBP1
    分子量
    7.3 kDa
    UniProt
    P05019
    途径
    RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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