CRHBP Protein (AA 25-322) (His tag)
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- 抗原 See all CRHBP 蛋白
- CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-322
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宿主
- 人
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资源
- 人细胞
- 标记
- This CRHBP protein is labelled with His tag.
- 原理
- Recombinant Human Corticotropin-Releasing Factor-Binding Protein/CRHBP (C-6His)
- 序列
- YLELREAADY DPFLLFSANL KRELAGEQPY RRALRCLDML SLQGQFTFTA DRPQLHCAAF FISEPEEFIT IHYDQVSIDC QGGDFLKVFD GWILKGEKFP SSQDHPLPSA ERYIDFCESG LSRRSIRSSQ NVAMIFFRVH EPGNGFTLTI KTDPNLFPCN VISQTPNGKF TLVVPHQHRN CSFSIIYPVV IKISDLTLGH VNGLQLKKSS AGCEGIGDFV ELLGGTGLDP SKMTPLADLC YPFHGPAQMK VGCDNTVVRM VSSGKHVNRV TFEYRQLEPY ELENPNGNSI GEFCLSGLVD HHHHHH
- 产品特性
- Recombinant Human Corticotropin-Releasing Factor-Binding Protein/CRHBP is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Tyr25-Leu322) of Human CRHBP fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CRHBP 蛋白
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Corticotropin Releasing Hormone Binding Protein (CRHBP) (AA 1-322) protein (GST tag)
CRHBP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Corticotropin Releasing Hormone Binding Protein (CRHBP) (AA 22-322) protein (His tag)CRHBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Corticotropin Releasing Hormone Binding Protein (CRHBP) protein (Myc-DYKDDDDK Tag)CRHBP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150mm NaCl, pH 7.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))
- 别名
- crhbp (CRHBP 产品)
- 别名
- crh-BP Protein, GB14094 Protein, zgc:91905 Protein, CRHBP Protein, CRH-BP Protein, CRF-BP Protein, CRFBP Protein, Crfbp Protein, crhbp-A Protein, gene E Protein, corticotropin releasing hormone binding protein Protein, corticotropin releasing hormone binding protein S homeolog Protein, CRHBP Protein, crhbp Protein, crh-BP Protein, Crhbp Protein, crhbp.S Protein
- Sub Type
- Fusionprotein
- 背景
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Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Difference between CRHBP from different species exist, human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy. CRHBP is presumed to either sequester CRH, rendering it unavailable to cells or transport it to target tissues. Although CRF-BP concentration in the human peripheral circulation is normally low, it increases throughout pregnancy and fall back rapidly after parturition.
Alternative Names: Corticotropin-Releasing Factor-Binding Protein, CRF-BP, CRF-Binding Protein, Corticotropin-Releasing Hormone-Binding Protein, CRH-BP, CRHBP, CRFBP - 分子量
- 34.38 kDa
- UniProt
- P24387
- 途径
- Negative Regulation of Hormone Secretion
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