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PRPH2 产品

(Peripherin 2 (Retinal Degeneration, Slow) (PRPH2))

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008].

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Featured PRPH2 Categories

PRPH2 抗体

High quality antibodies with extensive validation data.

PRPH2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRPH2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, ICC, IHC
Validations
  • (2)
Cat. No. ABIN6264450
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN519715
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p), ELISA, ICC, IHC (fro), IHC (p)
Validations
Cat. No. ABIN1385179
Quantity 100 μL
Datasheet Datasheet

Recommended PRPH2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234138
Quantity 96 tests
Datasheet Datasheet

Recommended PRPH2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330435
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3097022
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133051
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PRPH2 Products

Robertson, Doroudchi, Nguyen, Durham, Strong, Shaw, Julien, Mushynski: "A neurotoxic peripherin splice variant in a mouse model of ALS." in: The Journal of cell biology, Vol. 160, Issue 6, pp. 939-49, (2003) (PubMed).

Synonyms and alternative names related to PRPH2

peripherin 2 (Prph2), peripherin 2 (PRPH2), peripherin 2 (retinal degeneration, slow) S homeolog (prph2.S), AOFMD, AVMD, CACD2, CRDS1, DS, Nmf193, PRPH, prph-2, prph2b, Rd-2, Rd2, rd2, Rds, rds, RDS, rds38, RP7, RSRDS, Tspan22, TSPAN22

Protein level used designations for PRPH2

  • peripherin-2
  • retinal degeneration 2
  • retinal degeneration slow protein
  • retinal degeneration, slow (retinitis pigmentosa 7)
  • retinal degeneration, slow
  • peripherin 2, homolog of mouse
  • peripherin, photoreceptor type
  • retinal peripherin
  • tetraspanin-22
  • tspan-22
  • retinitis pigmentosa 7
  • photoreceptor outer segment membrane glycoprotein 1
  • peripherin protein
  • rds gene for peripherin
  • peripherin 2 (retinal degeneration, slow) b
  • xRDS38
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