Protein tyrosine Phosphatase, Receptor Type, J 抗体
(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
PTPRJ 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
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Find Protein tyrosine Phosphatase, Receptor Type, J 抗体 for a variety of species such as anti-Human Protein tyrosine Phosphatase, Receptor Type, J, anti-Mouse Protein tyrosine Phosphatase, Receptor Type, J, anti-Rat Protein tyrosine Phosphatase, Receptor Type, J. The species listed below are among those available. Click on a link to go to the corresponding products.
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Popular Protein tyrosine Phosphatase, Receptor Type, J 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7441778
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN7440614
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193257
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN7193256
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
- (2)
Cat. No.
ABIN742170
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7167504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
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Cat. No.
ABIN562534
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
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Cat. No.
ABIN1043031
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (2)
Cat. No.
ABIN2749044
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (2)
Cat. No.
ABIN2749107
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN5014202
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN655037
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN3013367
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (1)
Cat. No.
ABIN1111109
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
Cat. No.
ABIN742172
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Protein tyrosine Phosphatase, Receptor Type, J 抗体
: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." in: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." in: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).
: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." in: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).
: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." in: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).
: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." in: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).
: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).
: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).
: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).
: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." in: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).
: "Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers." in: Nature genetics, Vol. 31, Issue 3, pp. 295-300, (2002) (PubMed).
Aliases for Protein tyrosine Phosphatase, Receptor Type, J 抗体
acid phosphatase 1 (ACP1) 抗体protein tyrosine phosphatase, receptor type J (PTPRJ) 抗体
protein tyrosine phosphatase, receptor type, J (Ptprj) 抗体
protein tyrosine phosphatase, receptor type, J (PTPRJ) 抗体
protein tyrosine phosphatase, receptor type, J (EUBREC_2762) 抗体
AI450271 抗体
BET 抗体
Byp 抗体
CD148 抗体
DEP-1 抗体
DEP1 抗体
HAAP 抗体
HPTPeta 抗体
Ptpb2 抗体
PTPbeta2 抗体
PTPRJ 抗体
R-PTP-ETA 抗体
RPTPJ 抗体
Scc-1 抗体
SCC1 抗体
Scc1 抗体
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